Infections and Immunology

  • About the area
  • Groups

The Research Area in Infections and Immunology is created to bring together translational research in inflammatory and infectious diseases, clinical microbiology and immunology, with the aim of optimizing the diagnosis, treatment, prognosis and prevention of diseases. infectious. This area actively contributes to the surveillance of health problems arising from the infection and its prevention.

This area is made up of four groups, which investigate infectology, inflammatory diseases, critically ill patients and airway pathology.

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of infections prevalent in our environment, and, specifically, zoonoses, HIV infection, endocarditis, bacterial resistance and health-related illnesses.

The Research Group on Inflammatory Joint Disease, Bone Metabolism and Systemic Autoimmune Diseases is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases. The Group's research focuses on the mechanisms of inflammation and their repercussions. The Group works in psoriatic arthritis, spondyloarthritis, articular cartilage abnormalities, bone metabolism, inflammatory bowel disease and systemic disease.

The Critical Patient Translational Research Group studies the respiratory and cardiovascular pathophysiology of the critical patient. It approaches the study of this subject from an integral and patient-centered perspective. The Group develops preclinical and clinical research projects, and incorporates engineers, with whom it develops technology applied to monitoring.

The Research Group on Airway Inflammation and Sleep Pathology is made up of researchers specializing in pneumology, microbiologists and biologists involved in individual and multicenter projects, both nationally and internationally. The Group has active lines of research in COPD, lung cancer, respiratory microbiome, pulmonary fibrosis, inflammation in asthma, and comorbidities and multidisciplinary care in respiratory sleep disorders.

Area coordination
Eduard Monsó Molas

emonso@tauli.cat

Group A8G1 - Study group on community and healthcare-related infections

Accreditation level: Consolidation phase

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of some of the most prevalent infections in our environment since the 80s within a common framework, specifically, diseases related to medical care, zoonoses and HIV infection, from an epidemiological, clinical and therapeutic perspective. In order to answer all the questions raised, the group is made up of a multidisciplinary team that includes nurses, pharmacists, veterinarians, epidemiologists and psychologists working in Parc Taulí. Most of them also have teaching responsibilities at the Autonomous University of Barcelona.

For years this group has received public financial support to carry out competitive projects, under the leadership of Dr. Ferran Segura, and since 2016, by Dr. Oriol Gasch. It is currently accredited as a Consolidated Research Group of the Generalitat de Catalunya (AGAUR; SGR, 2017-677).

Lines of research

  • Study of antibiotic resistance
  • Study of healthcare associated infections (IRAS).
  • Study of infectious endocarditis.
  • Study of human immunodeficiency virus infection
  • Study of zoonoses

Composition of the group

Oriol Gasch Blasi (Group leader)

Doctors

  • Amengual Guedan, M. José
  • Capilla Rubio, Silvia
  • Diaz Santos, Emilio
  • Falgueras López, Lluís
  • Gomila Grange, Aina
  • Navarro Vilasaró, Marta
  • Quijada Pich, Óscar

Predoctoral

  • Bierge Cabrera, Paula
  • Machado Sicilia, M. Luisa
  • Sanfeliu Sala, Isabel

Non-Doctoral Researchers

  • Calzado Isbert, Sònia
  • Casabella Pernas, Antonio
  • Cervantes García, Manel
  • Espasa Soley, Mateu
  • Van den Eynde Otero, Eva

Group A8G2 - Inflammatory joint disease, bone metabolism and systemic autoimmune diseases

Accreditation level: Consolidation

The research group is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases in a multidisciplinary way.

Our research focuses on studying the mechanisms of inflammation in different systemic autoimmune rheumatic diseases and their repercussions on joint destruction and bone metabolism. In this sense, we study the prognostic and predictive factors of response to treatment to improve the evolution of these diseases. We evaluate the response to biological therapy of different diseases. We have multidisciplinary teams to evaluate and develop care and research protocols for psoriatic arthritis, hydrosadenitis, uveitis and inflammatory bowel disease.

Lines of research

  • Systemic autoimmune rheumatic diseases
  • Spondyloarthritis
  • Inflammation and articular cartilage
  • Inflammation and bone metabolism
  • Inflammation and skin (hydrosadenitis and psoriasis)
  • Systemic autoimmune diseases (MDI)

Composition of the group

Jordi Gratacós Masmitjà (Group leader)

Doctors

  • Calvet Fontova, Joan
  • Delgado de la Poza, Juan Francisco
  • Graell Martín, Eduard
  • Marí Alfonso, Begoña
  • Moreno Martínez-Losa, Mireia
  • Oristrell Salvà, Joaquim
  • Ribera Pibernat, Miquel
  • Romaní de Gabriel, Jorge
  • Tolosa Vilella, Carles

Predoctoral

  • Arévalo Salaet, Marta
  • Casado Burgos, Enrique
  • Galisteo Lencastre, Carlos
  • García Manriquez, María
  • Gómez Centeno, Antonio
  • Llop Vilaltella, Maria
  • Morera Morales, Maria Lluïsa
  • Orellana Garrido, Cristobal

Non-Doctoral Researchers

  • Luelmo Aguilar, Jesús

Support professionals

  • Roig Farré, Alba
  • Serrano Suárez, Alejandra

Group A8G3 - Translational research in the critically ill patient

Accreditation level: Consolidation

Our lines are oriented to translational research in the field of pathophysiology associated with the critical patient and are focused on the study of respiratory and cardiovascular pathophysiology, sepsis and its management in the ICU. Our challenge over the next few years is to approach the study of critical patient-associated pathology from a broad, comprehensive, multidisciplinary, humanized and patient-centered perspective and to foster strategies that allow us to tailor treatments to our particular needs. and at the follow-up of these patients beyond discharge from the ICU (post-ICU syndrome).

The research team is multidisciplinary and is made up of researchers of different profiles, which allows the development of clinical and preclinical research projects. In parallel, and thanks to the incorporation of engineers, we work transversally in new technological developments applied to monitoring and therapeutic innovation. The team works on projects where digital transformation, large volumes of data and elements of artificial intelligence are common to all of them.

The preclinical research is complemented and carried out in parallel with the clinical studies carried out in ICU patients, favoring the translational perspective. We work on the development of experimental models that recreate pathologies associated with the critically ill (SDRA, LPA, sepsis), both in vivo (animal models) and in vitro (cell cultures).

Lines of research

  • Respiratory pathophysiology in the critical patient.
  • Cardiovascular dysfunction, hemodynamic monitoring and sepsis in the critical patient.
  • Humanization.
  • Collection and processing of biomedical signals.
  • Artificial intelligence applied to dynamic physiological signals.
  • Experimental models and associated treatments.

Composition of the group

Josefina López Aguilar (Group leader)

Doctors

  • Artigas Raventós, Antoni
  • Blanch Torra Lluís
  • Camprubí Rimblas, Marta
  • De Haro López, Candelaria
  • Fernández Gonzalo, M. Soledad
  • Lujan Torné, Manel
  • Mesquida Febrer, Jaume
  • Ochagavía Calvo, Ana
  • Sarlabous Uranga, Leonardo

Predoctoral

  • Aquino Esperanza, José
  • Areny Balaguero, Aina
  • Navarra Ventura, Guillem
  • Morales Quintero, Luís

Non-Doctoral Researchers

  • Martí Hereu, Lídia

Support professionals

  • Gomà Fernández, Gemma

Associated professionals

  • Espinal Sacristan Cristina
  • Fortià Palahi, Cristina
  • Gruartmoner de Vera, Guillem
  • Navas Pérez, Ana
  • Ridao Sais, Natalia
  • Rodríguez Yakushev, Andrey Luis
  • Torrents Lara, Eva

Group A8G4 - Inflammation of the airways and sleep pathology

Accreditation level: Consolidation

Our team is made up of researchers specializing in pulmonology, microbiologists and biologists involved in individual and multicenter projects, both nationally and internationally. Our group works closely with the Infectious and Respiratory Diseases research group at the Germans Trias i Pujol Hospital. We are part of the Centro de Investigación Biomédica en Red Enfermedades Respiratorias (cyber) research network, and we are recognized as a Consolidated Research Group by the Generalitat de Catalunya (AGAUR: 2014 SGR 801).

Our group actively participates in the Corporate Research Program (PCI) for cyber within the lines of research in COPD, pneumonia and lung cancer. Within this last line, we collaborate with the international staging register of the IASLC *, centralizing the Cyber ​​Pulmonary Biobank. Finally, we also investigated immunomodulatory therapy of inflammation in persistent asthma, respiratory sleep disorders, and chronic interstitial lung disease.

* International Association for the Study of Lung Cancer

Lines of research

  • Inflammation and repair in respiratory disease
  • Microbiome in chronic respiratory diseases
  • Ventilatory sleep disorders

Composition of the group

Eduard Monsó Molas (Group leader)

Doctors

  • Cardesín Revilla, Alda
  • Domingo Ribas, Christian
  • Gallego Diaz, Miguel
  • García Núñez, Marian
  • Masdeu Margalef, M. José
  • Montón Soler, Concepción
  • Moreno Gómez de Bonilla, Amàlia
  • Pomares Amigo, Xavier
  • Sogo Sagardia, Ana
  • Vigil Giménez, Laura

Predoctoral

  • Grimau Chapinal, Carles
  • Lalmolda Puyol, Cristina

Non-Doctoral Researchers

  • Estela Esteve, Júlia
  • Mateu Vives, Georgina
  • Monserrate Mitchell, Daniel-Ross

Support professionals

  • Arranz Cardaba, María Isabel
  • Galera Inverno, Ana
  • Noray Malgrat, Mariona
  • Ramírez Prat, Enriqueta
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