Infections and Immunology

  • About the area
  • Groups

The research area in Infections and Immunology is created to bring together translational research in inflammatory and infectious diseases, clinical microbiology and immunology, with the aim of optimizing the diagnosis, treatment, prognosis and prevention of infectious diseases. This area actively contributes to the surveillance of health problems arising from infection and its prevention.

This area is made up of four groups, which investigate infectology, inflammatory diseases, critically ill patients and airway pathology.

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of infections prevalent in our environment, and, specifically, zoonoses, HIV infection, infectious endocarditis, infections caused by multidrug-resistant microorganisms and health-related diseases.

The Research Group on Inflammatory Joint Disease, Bone Metabolism and Systemic Autoimmune Diseases is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases. The Group's research focuses on the mechanisms of inflammation and their repercussions. The Group works in psoriatic arthritis, spondyloarthritis, articular cartilage abnormalities, bone metabolism, inflammatory bowel disease and systemic disease.

The Critical Patient Translational Research Group studies the respiratory and cardiovascular pathophysiology of the critical patient. It approaches the study of this subject from an integral and patient-centered perspective. The Group develops preclinical and clinical research projects, and incorporates engineers, with whom it develops technology applied to monitoring.

The Research Group on Airway Inflammation and Sleep Pathology is made up of researchers specializing in pulmonology, microbiologists and biologists involved in individual and multicenter projects, both nationally and internationally. The group has lines of research active in COPD, lung cancer, respiratory microbiome, pulmonary fibrosis, inflammation in asthma, and comorbidities and multidisciplinary care in respiratory sleep disorders.

Strategic lines of the area

  • Application of genomics, microbiology and proteomics in clinical research.
  • Application of new technologies such as artificial intelligence or Big Data analysis to develop techniques for early diagnosis and support for clinical decision making.
  • New methodologies of network research work at different levels of care.
  • Search for new biomarkers for the diagnosis and treatment of infectious, immune and inflammatory diseases.
Area coordination
Eduard Monsó Molas

emonso@tauli.cat

Group A8G1 - Study group on community and healthcare-related infections

Accreditation level: Consolidated group

2017 SGR 677

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of some of the most prevalent infections in our environment since the 80s within a common framework, specifically, diseases related to medical care, zoonoses and HIV infection, from an epidemiological, clinical and therapeutic perspective. In order to answer all the questions raised, the group is made up of a multidisciplinary team that includes nurses, pharmacists, veterinarians, epidemiologists and psychologists working in Parc Taulí. Most of them also have teaching responsibilities at the Autonomous University of Barcelona.

For years this group has obtained public financial support to carry out competitive projects, under the leadership of Dr. Ferran Segura, and since 2016, Dr. Oriol Gasch. It is currently accredited as a consolidated research group of the Generalitat de Catalunya (AGAUR; SGR, 2017-677).

Lines of research

  • Epidemiology of antibiotic resistance from the perspective of One Health.
  • Study of healthcare associated infections (IRES).
  • Study of infectious endocarditis.
  • Study of human immunodeficiency virus (HIV) infection.

Composition of the group

Oriol Gasch Blasi (Group leader) | ORCID

Doctoral research staff

  • Amengual Guedan, M. José
  • Capilla Rubio, Silvia
  • Diaz Santos, Emilio
  • Gomila Grange, Aina
  • Brown Puigdueta, Anna
  • Mujal Martínez, Abel
  • Navarro Rubio, Gema
  • Navarro Vilasaró, Marta
  • Jaw Pich, Oscar
  • Sanfeliu Sala, Isabel
  • Van den Eynde Otero, Eva

Predoctoral

  • Barley Bay, Laia
  • Bierge Cabrera, Paula
  • Calzado Isbert, Sònia

Non-doctoral research staff

  • Sheriff Guillen, Marina
  • Casabella Pernas, Antonio
  • Cervantes García, Manel
  • Sword Sun, Matthew
  • Machado Sicilia, M. Luisa
  • Pedrosa Aragon, Marc

Group A8G2 - Inflammatory joint disease, bone metabolism and systemic autoimmune diseases

Accreditation level: Consolidation

The research group is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases in a multidisciplinary way.

Our research focuses on studying the mechanisms of inflammation in different systemic autoimmune rheumatic diseases and their repercussions on joint destruction and bone metabolism. In this sense, we study the prognostic and predictive factors of response to treatment to improve the evolution of these diseases. We evaluate the response to biological therapy of different diseases. We have multidisciplinary teams to evaluate and develop care and research protocols for psoriatic arthritis, hydrosadenitis, uveitis and immunomediated inflammatory disease (IMID) in dermatology.

Lines of research

  • Systemic autoimmune rheumatic diseases
  • Spondyloarthritis
  • Inflammation and articular cartilage
  • Inflammation and bone metabolism
  • Inflammation and skin (hydrosadenitis and psoriasis)
  • Systemic autoimmune diseases (MDI)

Composition of the group

Jordi Gratacós Masmitjà (Group leader) | ORCID

Doctoral research staff

  • Arevalo Salaet, Marta
  • Calvet Fontova, Joan
  • Delgado de la Poza, Juan Francisco
  • Graell Martín, Eduard
  • Wolf Vilaltella, Maria
  • Moreno Martínez-Losa, Mireia
  • Oristrell Salvà, Joaquim
  • Ribera Pibernat, Miquel
  • Romaní de Gabriel, Jorge
  • Tolosa Vilella, Carles
  • Gallego Moreno, Xavier

Predoctoral

  • Married Burgos, Enrique
  • Galisteo Lencastre, Carlos
  • Garcia Cirera, Sílvia
  • García Manríquez, María
  • Gómez Centeno, Antonio
  • Julià Agulló, Brother
  • Marí Alfonso, Begoña
  • Morera Morales, Maria Lluïsa
  • Orellana Garrido, Cristobal

Non-doctoral research staff

  • Blanch Ruda, Núria
  • Costa and Moya, Ester
  • Gómez Gallego, Rafael
  • Julia Agullo, German
  • Luelmo Aguilar, Jesús

Support professionals

  • Berenguer Llergo, Antoni
  • Llobell Uriel, Arturo
  • Serrano Suarez, Alejandra L.
  • Roig Farre, Alba
  • Rusiñol Gonzalez, Menna

Group A8G3 - Translational research in the critically ill patient

Accreditation level: Consolidated group

2017 SGR 955

Our lines are oriented to translational research in the field of pathophysiology associated with the critical patient and are focused on the study of respiratory and cardiovascular pathophysiology, sepsis and its management in the ICU. Our challenge over the next few years is to approach the study of critical patient-associated pathology from a broad, comprehensive, multidisciplinary, humanized and patient-centered perspective and to foster strategies that allow us to tailor treatments to our particular needs. and at the follow-up of these patients beyond discharge from the ICU (post-ICU syndrome).

The research team is multidisciplinary and is made up of researchers of different profiles, which allows the development of clinical and preclinical research projects. In parallel, and thanks to the incorporation of engineers, we work transversally in new technological developments applied to monitoring and therapeutic innovation. The team works on projects where digital transformation, large volumes of data and elements of artificial intelligence are common to all of them.

The preclinical research is complemented and carried out in parallel with the clinical studies carried out in ICU patients, favoring the translational perspective. We work on the development of experimental models that recreate pathologies associated with the critically ill (SDRA, LPA, sepsis), both in vivo (animal models) and in vitro (cell cultures).

Lines of research

  • Respiratory pathophysiology in the critical patient.
  • Cardiovascular dysfunction, hemodynamic monitoring and sepsis in the critically ill patient.
  • Characterization and management of Intensive Post-Care Syndrome (PICS).
  • Capture and processing of biomedical signals. Artificial intelligence applied to dynamic physiological signals.
  • Experimental models and treatments associated with critical pathology.

Composition of the group

Josefina López Aguilar (Group leader) | ORCID

Doctoral research staff

  • Artigas Raventós, Antoni
  • Blanch Torra Lluís
  • Camprubí Rimblas, Marta
  • De Haro López, Candelaria
  • Fernández Gonzalo, M. Soledad
  • Gruartmoner de Vera, Guillem
  • Lujan Torné, Manel
  • Mesquida Febrer, Jaume
  • Ochagavía Calvo, Ana
  • Sarlabous Uranga, Leonardo

Predoctoral

  • Aquino Esperanza, José
  • Areny Balaguero, Aina
  • Morales Quinteros, Luis
  • Navarra Ventura, Guillem

Non-doctoral research staff

  • Boneta Camí, Mireia
  • Estela Esteve, Júlia
  • List Arias, Eva
  • Martí Hereu, Lídia
  • Nogales Herranz, Sara

Support professionals

  • Gomà Fernández, Gemma

Associated professionals

  • Espinal Sacristan Cristina
  • Fortià Palahi, Cristina
  • Ridao Sais, Natalia
  • Rodríguez Yakushev, Andrey Luis

Students

  • Campaign Duel, Elena

Group A8G4 - Inflammation of the airways and sleep pathology

Accreditation level: Consolidated group

2017 SGR 716

Our team is made up of researchers specializing in pulmonology, microbiology and biology who participate in individual and multicenter projects, both nationally and internationally. Our group works closely with the Infectious and Respiratory Diseases research group at the Germans Trias i Pujol Hospital. We are part of the Research Network for Biomedical Research in the Respiratory Diseases Network (CIBERES), and we are recognized as a Consolidated Research Group by the Generalitat de Catalunya (AGAUR: 2014 SGR 801).

Our group actively participates in the CIBER Corporate Research Program (PCI) within the lines of research in COPD, pneumonia and lung cancer. Within this last line, we collaborate with the international staging register of the IASLC *, centralizing the CIBERES Pulmonary Biobank. Finally, we also investigated immunomodulatory therapy of inflammation in persistent asthma, respiratory sleep disorders, and chronic interstitial lung disease.

* International Association for the Study of Lung Cancer

Lines of research

  • Research and search for biomarkers in inflammation and tissue repair in respiratory disease.
  • Microbiome in chronic respiratory diseases.
  • Ventilatory sleep disorders.

Composition of the group

Eduard Monsó Molas (Group leader) | ORCID

Doctoral research staff

  • Cardesín Revilla, Alda
  • Domingo Ribas, Christian
  • Gallego Diaz, Miguel
  • Masdeu Margalef, M. José
  • Montón Soler, Concepción
  • Moreno Gómez de Bonilla, Amàlia
  • Pomares Amigo, Xavier
  • I want Blanca, Sara
  • Sogo Sagardia, Ana
  • Vigil Giménez, Laura

Predoctoral

  • Grimau Chapinal, Carles
  • Lalmolda Puyol, Cristina
  • Monserrate Mitchell, Daniel-Ross

Support professionals

  • Arranz Cardaba, María Isabel
  • Noray Malgrat, Mariona
  • Ramírez Prat, Enriqueta
  • Setó Gorg, Laia

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