Infections and Immunology

  • About the area
  • Groups

The research area in Infections and Immunology is created to bring together translational research in inflammatory and infectious diseases, clinical microbiology and immunology, with the aim of optimizing the diagnosis, treatment, prognosis and prevention of infectious diseases. This area actively contributes to the surveillance of health problems arising from infection and its prevention.

This area is made up of four groups, which investigate infectology, inflammatory diseases, critically ill patients and airway pathology.

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of infections prevalent in our environment, and, specifically, zoonoses, HIV infection, infectious endocarditis, infections caused by multidrug-resistant microorganisms and health-related diseases.

The Research Group on Inflammatory Joint Disease, Bone Metabolism and Systemic Autoimmune Diseases is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases. The Group's research focuses on the mechanisms of inflammation and their repercussions. The Group works in psoriatic arthritis, spondyloarthritis, articular cartilage abnormalities, bone metabolism, inflammatory bowel disease and systemic disease.

The Critical Patient Translational Research Group studies the respiratory and cardiovascular pathophysiology of the critical patient. It approaches the study of this subject from an integral and patient-centered perspective. The Group develops preclinical and clinical research projects, and incorporates engineers, with whom it develops technology applied to monitoring.

The Research Group on Airway Inflammation and Sleep Pathology is made up of researchers specializing in pulmonology, microbiologists and biologists involved in individual and multicenter projects, both nationally and internationally. The group has lines of research active in COPD, lung cancer, respiratory microbiome, pulmonary fibrosis, inflammation in asthma, and comorbidities and multidisciplinary care in respiratory sleep disorders.

Strategic lines of the area

  • Application of genomics, microbiology and proteomics in clinical research.
  • Application of new technologies such as artificial intelligence or Big Data analysis to develop techniques for early diagnosis and support for clinical decision making.
  • New methodologies of network research work at different levels of care.
  • Search for new biomarkers for the diagnosis and treatment of infectious, immune and inflammatory diseases.
Area coordination
Jordi Gratacós Masmitjà

Group A8G1 - Study group on community and healthcare-related infections

Accreditation level: Consolidated group

GRC 2021 SGR 01439

The Study Group on Community and Healthcare Related Infections aims to study the pathogenic mechanisms of some of the most prevalent infections in our environment since the 80s within a common framework, specifically, diseases related to medical care, zoonoses and HIV infection, from an epidemiological, clinical and therapeutic perspective. In order to answer all the questions raised, the group is made up of a multidisciplinary team that includes nurses, pharmacists, veterinarians, epidemiologists and psychologists working in Parc Taulí. Most of them also have teaching responsibilities at the Autonomous University of Barcelona.

For years this group has obtained public financial support to carry out competitive projects, under the leadership of Dr. Ferran Segura, and since 2016, Dr. Oriol Gasch. It is currently accredited as a consolidated research group of the Generalitat de Catalunya (AGAUR; SGR, 2017-677).

Lines of research

  • Epidemiology of antibiotic resistance from the perspective of One Health.
  • Study of healthcare associated infections (IRES).
  • Study of infectious endocarditis.
  • Study of human immunodeficiency virus (HIV) infection.

Composition of the group

Oriol Gasch Blasi (Co-Head of Group) | ORCID
Óscar Quijada Pich (Co-Head of Group) | ORCID

Doctoral research staff

  • Capilla Rubio, Silvia
  • Diaz Santos, Emilio
  • Gomila Grange, Aina
  • Marrón Puigdueta, Anna
  • Mujal Martínez, Abel
  • Navarro Rubio, Gema
  • Navarro Vilasaró, Marta
  • Sánchez Osuna, Miquel
  • Van den Eynde Otero, Eva


  • Barley Bay, Laia
  • Bierge Cabrera, Paula
  • Calzado Isbert, Sònia
  • Monsálvez Martínez, Víctor

Non-doctoral research staff

  • Alguacil Guillen, Marina
  • Casabella Pernas, Antonio
  • Cervantes García, Manel
  • Espasa Soley, Mateu
  • Fidalgo Pardo, Berta
  • Gómez Sánchez, Immaculada
  • Machado Sicilia, M. Luisa
  • Monsálvez Martínez, Víctor
  • Pedrosa Aragón, Marc
  • Rosich Peris, Pilar

Group A8G2 - Inflammatory joint disease, bone metabolism and systemic autoimmune diseases

Accreditation level: Consolidation

GRC 2021 SGR 01363

The research group is made up of professionals from various medical specialties who collaborate in the study of joint and autoimmune diseases in a multidisciplinary way.

Our research focuses on studying the mechanisms of inflammation in the different systemic autoimmune rheumatic diseases and their repercussions on joint destruction and bone metabolism. In this sense, we study the prognostic and predictive factors of response to treatment to improve the evolution of these diseases. We evaluate the response to biological therapy for different diseases. We have multidisciplinary teams to evaluate and develop care and research protocols for psoriatic arthritis, hidradenitis, uveitis and immune-mediated inflammatory disease (IMID) in dermatology.

Research lines

  • Systemic autoimmune rheumatic diseases
  • Spondyloarthritis
  • Inflammation and articular cartilage
  • Inflammation and bone metabolism
  • Inflammation and skin (hidrosadenitis and psoriasis)
  • Systemic autoimmune diseases (MDI)

Composition of the group

Jordi Gratacós Masmitjà (Co-head of group) | ORCID

Joan Calvet Fontova (Co-head of group) | ORCID

Doctoral research staff

  • Arévalo Salaet, Marta | ORCID
  • Esteve Valverde, Enrique
  • García Manríquez, María
  • Gómez Centeno, Antonio | ORCID
  • Graell Martín, Eduard | ORCID
  • Llop Vilaltella, Maria | ORCID
  • Marí Alfonso, Begoña
  • Mercadé Torras, Joan Maria
  • Moreno Martínez-Losa, Mireia | ORCID
  • Orellana Garrido, Cristobal
  • Oristrell Salvà, Joaquim – Investigador emèrit
  • Ribera Pibernat, Miquel | ORCID


  • Casado Burgos, Enrique | ORCID
  • Delgado de la Poza, Juan Francisco | ORCID
  • Feijoo Massó, Carlos
  • Galisteo Lencastre, Carlos | ORCID
  • Garcia Cirera, Sílvia
  • Julià Agulló, Germà

Non-doctoral research staff

  • Aymerich Mañas, Cristina
  • Cabanillas Paredes, Montse
  • Garbayo Salmons, Patricia
  • García Pinilla, Alba
  • Luelmo Aguilar, Jesús
  • Riera Martí, Núria | ORCID
  • Rusiñol Gonzalez, Menna

Support professionals

  • Berenguer Llergo, Antoni | ORCID
  • Blanch Ruda, Núria
  • Carreras Nolla, Anna | ORCID
  • Feliu Hernández, Clara| ORCID
  • Gómez Gallego, Rafael
  • Llobell Uriel, Arturo
  • Pedraza Cabeza, Ana
  • Rodrigo Pares, Albert
  • Roig Farre, Alba
  • Saus Martínez, Ester | ORCID
  • Serrano Suarez, Alejandra L.

Associated professionals

  • Esplugues Clos, Joan
  • López Góngora, Sheila
  • Mas Maresma, Laia

Outstanding projects


MOMPRUAA is a national, multicenter project that aims to increase the predictive capacity to anticipate the risk of recurrent uveitis (acute anterior uveitis UAA) in patients with ankylosing spondylitis (AS).


The BARITONE project aims to promote the digitization of the health care value chain, with special emphasis on the exploitation of data by clinical staff, researchers and Artificial Intelligence scientists, to improve patient care .


The OASIS project aims to develop a high-capacity tool integrating a large amount of information from multiple and diverse sources, based on artificial intelligence, to comprehensively obtain a better diagnostic and prognostic approach in patients with osteoarthritis .


The SERHA project aims to study senescence, that is, cellular aging in patients with rheumatoid arthritis and its influence on the pathophysiology of the disease. This study will help us look for a new approach to the treatment of the disease based on the patients' own serum, enriched in cytokines.

Group A8G3 - Translational research in the critically ill patient

Accreditation level: Consolidated group

GRC 2021 SGR 01376

Our lines are oriented to translational research in the field of pathophysiology associated with the critical patient and are focused on the study of respiratory and cardiovascular pathophysiology, sepsis and its management in the ICU. Our challenge over the next few years is to approach the study of critical patient-associated pathology from a broad, comprehensive, multidisciplinary, humanized and patient-centered perspective and to foster strategies that allow us to tailor treatments to our particular needs. and at the follow-up of these patients beyond discharge from the ICU (post-ICU syndrome).

The research team is multidisciplinary and is made up of researchers of different profiles, which allows the development of clinical and preclinical research projects. In parallel, and thanks to the incorporation of engineers, we work transversally in new technological developments applied to monitoring and therapeutic innovation. The team works on projects where digital transformation, large volumes of data and elements of artificial intelligence are common to all of them.

The preclinical research is complemented and carried out in parallel with the clinical studies carried out in ICU patients, favoring the translational perspective. We work on the development of experimental models that recreate pathologies associated with the critically ill (SDRA, LPA, sepsis), both in vivo (animal models) and in vitro (cell cultures).

Lines of research

  • Respiratory pathophysiology in the critical patient.
  • Cardiovascular dysfunction, hemodynamic monitoring and sepsis in the critically ill patient.
  • Characterization and management of Intensive Post-Care Syndrome (PICS).
  • Capture and processing of biomedical signals. Artificial intelligence applied to dynamic physiological signals.
  • Experimental models and treatments associated with critical pathology.

Composition of the group

Josefina López Aguilar (group co-IP) | ORCID

Oriol Roca Gas (group co-IP) | ORCID

Doctoral research staff

  • Artigas Raventós, Antoni
  • Blanch Torra Lluís
  • Camprubí Rimblas, Marta
  • Ceccato, Adrian
  • From Haro López, Candelaria
  • Fernández Gonzalo, M. Soledad
  • García García de Acilu, Marina
  • Navarra Ventura, Guillem
  • Sarlabous Uranga, Leonardo
  • Suñol Galofré, Francesc


  • Areny Balaguero, Aina
  • Campaign Duel, Elena
  • Estela Esteve, Julia
  • Godoy González, Marta
  • Morales Quinteros, Luis

Non-doctoral research staff

  • Gual Sánchez, Maria
  • Martí Hereu, Lídia
  • Santafé Colomina, Manel
  • Santos Pulpon, Veronica

Support professionals

  • Gomà Fernández, Gemma

Associated professionals

  • Fortià Palahi, Cristina
  • Ridao You know, Natalia
  • Rodríguez Yakushev, Andrey Luis

Outstanding projects


Characterization of the profile of Post Intensive Care Syndrome or PICS (from the English Post Intensive Care Syndrome) in the survivor of critical illness due to COVID-19.


TESAI Care is a spin-off of the VHIR and the I3PT that has designed heecap which is a system to promote the respiratory recovery of patients under invasive mechanical ventilation. heecap provides non-invasive electrical stimulation of the respiratory muscles in synchronization with the patients breathing.

Better Care

Better Care is a spin-off incorporated in 2010 that offers medical device integration and clinical data analysis solutions. BC Link® is a software that allows you to connect, integrate and analyze the data of monitored patients. It provides a continuous flow of data between medical devices and information systems.

Group A8G4 – Airway inflammation, sleep and ventilation pathology

Accreditation level: Consolidated group

GRC 2021 SGR 01547 (I3PT - IGTP)

Our team consists of researchers specializing in pulmonology, microbiologists and biologists who participate in individual and multicenter projects, both nationally and internationally. Within the group's research lines, in the infection research line, we work closely with the Infectious and Respiratory Diseases research group at Germans Trias i Pujol Hospital. In the ventilation line, strategic alliances have been established with national and international groups (University of Barcelona, ​​SOMNO-NIV group, University of Rouen). Also, in the asthma line, we work in collaboration with leading national and international groups. Finally, the line of sleep is recognized nationally and internationally as excellence in research. In addition, we are part of the research network Center for Biomedical Research in Respiratory Diseases Network (CIBERES), and we are recognized as a Consolidated Research Group by the Generalitat de Catalunya (AGAUR: 2014 SGR 801).

In the line of COPD and bronchiectasis, the line of chronic bronchial infection, the respiratory microbiome, infectious exacerbations and chronic treatment with azithromycin in the two chronic respiratory pathologies is particularly active. Finally, there are also lines active in inflammation in persistent asthma, sleep breathing disorders and chronic interstitial lung diseases

Lines of research

  • Artificial intelligence Artificial applied to non-invasive mechanical ventilation
  • Test bench models in non-invasive ventilation
  • Microbiome in chronic respiratory diseases.
  • Ventilatory sleep disorders.
  • COPD and chronic bronchial infection.
    o Treatment with chronic macrolides in COPD with recurrent exacerbations.
    o Nebulized/inhaled antibiotic treatment in COPD/Bronchiectasis.
    o Treatment with new modulators of the CFTR gene in Cystic Fibrosis.
  • Characterization of pulmonary hypertension in respiratory diseases.

Composition of the group

Manel Luján Torné (Group leader) | ORCID

Doctoral research staff

  • Cardesín Revilla, Alda
  • Domingo Ribas, Christian
  • Galician Diaz, Miguel
  • Lalmolda Puyol, Cristina
  • Masdeu Margalef, M. José
  • Montón Soler, Concepción
  • Monsó Molas, Eduard - Researcher Emeritus
  • Moreno Gómez de Bonilla, Amàlia
  • Pomares Amigo, Xavier
  • I want Blanca, Sara
  • Sogo Sagardia, Ana
  • Vigil Giménez, Laura


  • Bullich Ramon, Miriam
  • Flórez Solarana, Pablo
  • Grimau Chapinal, Carles
  • Monserrate Mitchell, Daniel-Ross
  • Prina, Elena
  • Ruiz Gemar, Inés

Non-doctoral research staff

  • Campos Motamayor, Mariana
  • Sansa Perna, Aina

Support professionals

  • Noray Malgrat, Mariona
  • Setó Gorg, Laia

Group A8G5 – Hemodynamics, microcirculation and tissue oxygenation research group in the critically ill patient (MiTOCrit)

Accreditation level: Popup group

The Research Group on Hemodynamics, microcirculation and tissue oxygenation in the critically ill patient (MiTOCrit) was born within the Translational Research Group in the critically ill patient, one of the main consolidated groups of the I3PT. The line opened more than 15 years ago, and has gradually taken on its own entity. The group has specialized in the study of microcirculatory alterations and the assessment of tissue oxygenation in different populations of critically ill patients, and is currently one of the leading groups in the field both nationally and internationally.

In this period of time, he has received various grants in both internal and public calls and from scientific societies. We will highlight the ISCIII projects of 2009 and 2019, as well as the research award of the European Society of Intensive Care Medicine 2009, and several research awards of the Catalan Society of Intensive Care Medicine. Since 2020, the group has consolidated a strategic alliance with the Institute of Photonic Sciences
(ICFO), which has led him to lead international studies, and to receive funding for different projects, highlighting a Horizon H2020 grant for the VASCOVID project in 2021, a La Marató 2021 project, and more recently the granting of a Marie grant Curie in the FLIGHT-COFUND program of the EU.

Beyond scientific production, reflected in the publication of more than 40 articles in indexed journals in this period, the group has produced 3 doctoral thesis works (Mesquida, Gruartmoner, Saludes) and currently has 3 doctoral thesis works registered (Espinal, Caballer and Nogales).

Lines of research

  • Tissue oxygenation in the critically ill patient with cardiovascular insufficiency
  • Study of endothelial function in different critical patient populations
  • Microcirculatory study in the process of disconnection from mechanical ventilation
  • Evaluation of the microcirculation in the hemodynamic resuscitation process

Composition of the group

Jaume Mesquida February (Group leader)

Doctoral research staff

  • Gruartmoner, Guillem
  • Mesquida, James


  • Knight, Alba
  • Nuts, Sara
  • Espinal, Cristina

Non-doctoral research staff

  • Gil, Aurora
  • Cortes, Edgar
  • Oller, Ferran
  • Prieto Jiménez, Eva

Outstanding projects


VASCOVID is a project funded by the Horizon 2020 program of the European Commission, whose main objective is to develop a device based on diffuse optics that allows the study of endothelial and microvascular function in patients with COVID19.

To achieve its goal, the VASCOVID consortium is made up of academic, industrial and clinical partners.


The research group is a member of the Barcelona Medical Photonics Network, whose mission is to promote the research and development activities in photonics that are being carried out in the Barcelona region through long-term collaborations between the ICFO and its biomedical and clinical partners.

The network annually holds conferences with its partners in order to share the development of research and innovation projects, and to create spaces for debate on photonics issues.

YouTubeThis content is blocked. Please review your Privacy Preferences.
Edit privacy / YouTube
Privacy preferences

When you visit our website, your browser may store information about specific services, usually in the form of cookies. Here you can change your privacy preferences. Please note that blocking certain types of cookies may affect your experience on our website and the services we offer.

Enable / disable Google Analytics tracking code
Enable / disable Google Fonts
Turn Google Maps on / off
Enable / disable embedded videos
This website uses cookies, mainly from third party services. You can edit your privacy preferences and / or accept the use of cookies.