Mental Health and Neuroscience

  • About the area
  • Groups
  • Mixed Unit

The Neuroscience and Mental Health research area is made up of a multidisciplinary group: psychiatry, neurology, psychology, neuropsychology, nursing, rehabilitation medicine, genetics and other research members with a common interest in improving knowledge and approach. of neurological and psychiatric diseases.

Within this objective, part of the studies have an epidemiological approach, with the interdisciplinary participation of professionals and different research methodologies. The groups develop studies in different areas (neurodegenerative diseases, schizophrenia, bipolar disorders, autism, depression, sleep pathology, epilepsy, neurovascular diseases, multiple sclerosis, genetically based developmental diseases) to improve the functionality and prevention of diseases. We also collaborate in different projects with the administration and national and international research groups in order to develop ICT and improve the transfer of these results to patients and professionals.

Based on this activity, the area has been recognized with two consolidated research groups and one pre-consolidated, by the Agency for the Management of University and Research Grants (AGAUR) of the Generalitat de Catalunya.

Research groups in the area of ​​Mental Health actively collaborate in national and international research networks. It is worth noting its recognition as a CIBERSAM Consolidated Group (CB19 / 09/00029) and the creation of the Mixed Unit with the Autonomous University of Barcelona in 2017, currently consolidated and developing translational and impact research projects.

Strategic lines of the area

  • Application of new digital technologies in the diagnosis and treatment of mental health pathologies.
  • Prevention and promotion of mental health in the young adult population.
  • Translational research for the development of specific markers and biomarkers for the diagnosis and treatment of mental health pathologies.
Area coordination
Narcís Cardoner Alvarez

ncardoner@tauli.cat

Group A3G4 - Affective disorders

Accreditation level: Consolidated group

2017 SGR 1292

TAINCO is a multidisciplinary group created in 2010, made up of clinical professionals and researchers, and led by Dr. Narcís Cardoner. The research conducted by TAINCO has focused on affective and anxiety disorders, mainly in the search for biomarkers of diagnosis, prognosis, progression and therapeutic response.

The aim of the group is to develop personalized psychiatry in these pathologies, lines converging with current projects developed at I3PT, aimed at enhancing and consolidating innovation and clinical research, as well as their integration into healthcare practice.

Some members of the group belong to the OCD Brain Imaging Consortium (OBIC), the Alliance and Research in ECT (CARE) clinic, the ENIGMA-Anxiety Consortium network, the ENIGMA-Antisocial Behavior, the Global ECT- * MRI Research Collaboration (GEMRIC)), the Society for Biological Psychiatry (SOBP), the European College of Neuropsychopharmacology (ECNP) and the European Psychiatric Association (EPA). Narcís Cardoner is the head of the scientific and organizational committee of the International Symposium on Current Issues and Controversies in Psychiatry and evaluator of proposals for European cooperation in science and technology (COST).

Lines of research

  • Detection and prevention strategies in affective disorders and anxiety: is framed mainly in relation to the European program for depression and suicide prevention. It evaluates predictive variables, socioeconomic cost as well as the effectiveness of containment strategies in the context of suicide prevention.
  • Innovation in the treatment of depression and anxiety disorders: evaluation, characterization and development of therapeutic strategies for the treatment of patients with these pathologies, currently focused on three fundamental therapeutic modalities.
  • Neurobiological markers of evolution and response to treatment in depression and anxiety disorders: work with different magnetic resonance imaging techniques (structural, functional, diffusion), in collaboration with the Bellvitge University Hospital (Hospitalet de Llobregat), the Germans Trias i Pujol Hospital (Badalona), as well as the Melbourne Neuropsychiatry Center Melbourne, Australia) and Massachusetts General Hospital (Boston, USA). It is closely related to the previous line.

Composition of the group

Narcís Cardoner Alvarez (Group leader) | ORCID

Doctoral research staff

  • Cano Català, Marta
  • Goldberg Hermo, Ximena
  • Rodriguez Pont, Anna
  • Coromina, Marta will go up

Predoctoral

  • Aguilar Fernández, Alfredo
  • Aguilar Morales, Eva
  • Bassa Mercadé, Adriana
  • Espelt Anfruns, Carme
  • Martínez Amoros, Erika
  • Massons Capdevila, Carme
  • Membrives Martin, Sonia
  • Navarra Ventura, Guillem
  • Porta Casteras, Daniel

Non-doctoral research staff

  • Crivilles Mas, Sara
  • Figuereo Rubio, Inés

Group A3G5 - E-mental health and epidemiology

Accreditation level: Consolidated group

2017 SGR 1412

Our original group has been the driving force behind the I3PT Neuroscience and Mental Health Area, promoting the development of other groups with which we work synergistically and in a network. Our group currently consists of a multidisciplinary team of psychology, psychiatry and nursing professionals.

Our group, recognized by the Generalitat de Catalunya (SGR 2017 1412), has been able to attract talent and form solid alliances with the INc-UAB, forming a group linked to the CIBERSAM network of ISCiii CB19 / 09/00029 led by the IP of the Group. On the other hand, he has promoted the constitution of the UAB Joint Unit for Translational Neuroscience, which he co-directs.

Our research is based on the epidemiological research of mental disorders, especially in primary care, study of risk factors from suicide (biological and psychosocial) and multilevel preventive interventions. Our group also studies the prevention and promotion of mental health at the child and adolescent level and the development, implementation and evaluation of e-Mental Health projects. Recently the group has integrated in the “Network of Innovation of New Technologies in Mental Health - TECSAM” (AGAUR-FEDER / Code: IU68- 013.943).

Lines of research

  • Studies for the prevention of depression and suicidal behaviors: clinical and biological factors that may have a potential predictive capacity for risk or therapeutic response in behaviors.
  • Epidemiology of mental disorders in Primary Care.
  • Development and validation of e-Mental Health projects.
  • Prevention and promotion of mental health for young people.

Composition of the group

Diego Palao Vidal (Group leader) | ORCID

Doctoral research staff

  • Álvarez Pedrero, Aida
  • Cánovas Verge, David
  • Cebrià Meca, Anabel
  • Fernández Gonzalo, M. Soledad
  • Fradera Jiménez, Marc
  • Granero Lázaro, Albert
  • Jodar Vicente, Mercè
  • Pamias Massana, Montserrat
  • Parra Uribe, Isabel
  • Sansa Fayos, Gemma

Predoctoral

  • Agustín Morras, Marta Raisa
  • Comendador Vázquez, Laura
  • Guinovart Julián, Martí
  • Merodio Ruiz, Igor
  • Pujals Altés, Elena
  • Reina López, Nuria

Non-doctoral research staff

  • Aguilar Morales, Eva
  • García Carreria, Carme
  • Gracia Liso, Rebeca
  • Hervàs Pujol, Mariona
  • Puntí Vidal, Joaquim

Associated professionals

  • Civil Espona, Xavier
  • Ribera Perpiña, Gisela
  • Villarrasa Millan, Antonia

Support professionals

  • Pardo Guerra, María

Group A3G6 - Psychoneuroendocrinology and Stress in Psychosis (PSICPNEC)

Accreditation level: Consolidated group

The group 'Psychoneuroendocrinology and stress in psychosis' (PSICPNEC) is composed of researchers from the Mental Health Service of Parc Taulí Hospital, some of whom are UAB professors. The main scientific interest of the group is to study the relationship between hormones and behavior (Psychoneuroendocrinology) in patients with a psychotic disorder. The lines of work include the study of the neurobiological mechanisms of stress (hypothalamus-pituitary-adrenal axis) in the etiopathogenesis and prognosis of psychotic disorders. The lines of research include the study of the role of hormones in the risk of transition to psychosis in vulnerable populations and the association with a more severe phenotype (eg, cognitive impairment) in established psychoses. Other lines are focused on the study of the role of gender and hormones in the therapeutic response to pharmacological, psychotherapeutic and cognitive rehabilitation interventions in psychotic disorders.

In recent years, the group has received competitive funding at European level (ERA-NET project on stress biomarkers in psychosis) and nationally (two FIS projects). Two researchers from the group have received an intensification of research activity for the PERIS strategy (Xavier Labad and Itziar Montalvo) and also for the Carlos III Institute of Health (Xavier Labad).

Lines of research

  • Biomarkers of stress and risk of developing a psychotic disorder.
  • Impact of hormones on the clinical expression of psychotic disorders.
  • Neurocognition and social cognition in emerging psychotic disorders: prognostic and therapeutic implications.
  • Psychopathological and biological consequences of abuse in adolescents and young adults.

Composition of the group

Xavier Labad Arias (Group leader) | ORCID

Doctoral research staff

  • Barbero Valverde, David
  • Cobo Gómez, Jesús
  • González Rodríguez, Alex
  • Montalvo Aguirrezabala, Itziar

Predoctoral

  • Crosas Armengol, Josep
  • Estrada Coma, Francesc
  • Ferrer Alberti, Alex
  • Gabernet Florensa, Rosa
  • Gago Quintela, Elena Estefania
  • Tost Bonet, Meritxell

Non-doctoral research staff

  • Aguayo Navarro, Raquel

Associated professionals

  • Acebillo Baque, Siddarta

La Translational Neuroscience Unit, set up in 2018, is a collaboration platform between clinical and basic researchers from the Parc Taulí Research and Innovation Institute (I3PT) and the UAB Institute of Neurosciences (INc-UAB). It is through this structure that the INCs recognizes the U3PT Neuroscience and Mental Health Area as an Associate Research Unit of the UAB.

The UAB Institute of Neurosciences (INc-UAB) is made up of neuroscientists who study how healthy and diseased brains work. The specialties of the more than 200 members of the INC research groups fall into the following strategic areas: Neurodegeneration and Aging, Neurodegeneration and Repair and Behavioral Neuroscience. The INC publishes more than 100 scientific articles a year in the most prestigious journals in Neuroscience and its researchers obtain public and private funding both nationally and internationally. In addition, we have services in Histology, cell culture, microscopy, behavior and stereotaxy that support researchers from our institute and other public and private institutions. Our main goals are excellence in the study of the nervous system, to promote translational research and to transfer this knowledge to society. In order to understand the basics of how the brain works we use both animal models, cell cultures, computational models, and human studies.

The objectives of the Translational Neuroscience Unit are:

  • Develop projects for improve the knowledge of the neurobiological basis of neuropsychiatric and neurological disorders by mixed research teams that carry out the clinical validation of the results obtained in basic research, the identification of biomarkers applicable to the detection, diagnosis, therapeutics and prognostic evaluation of these disorders.
  • Develop research projects that require systematic and efficient psychophysiological, neurophysiological and / or neurocognitive evaluation, in the study of neurodevelopmental disorders, neuropsychiatric disorders and the effects of psychoactive treatments.
  • Enhance the pre and postdoctoral teaching in translational neuroscience research, for the training of researchers of excellence.

Responsible

  • Diego J Palao Vidal

Members

  • Narcís Cardoner Alvarez
  • Javier Labad Arias
  • Montserrat Pamias Massana
  • Isabel Parra Uribe
  • Ana Roche Martínez
  • Montserrat Torras Tomorrow
  • Victoria Aldecoa Bilbao
  • Mercè Jodar Vicente
  • Gemma Sansa Fayos
  • David Cánovas Vergé
  • Mariona Hervas Pujol
  • Miriam Guitart Feliubadalo
  • Victor Pérez Riverola
  • Marta Subirà Corominas
  • Albert Granero Lázaro
  • Aída Álvarez Pedrero
  • Itziar Montalvo Aguirrezabala
  • Soledad Fernández Gonzalo
  • Ximena Goldberg Hermo
  • Annabel Cebrià Meca
  • Joan Visa Bombardment

Responsible

  • A hard tackle from Jesús Giraldo to Arjonilla

Members

  • Raül Andero Gali
  • Antonio Armario García
  • Carlos Barcia González
  • José R. Bayascas Ramírez
  • Esther Dalfó Capella
  • Albert Fernández Teruel
  • Lydia Giménez Llort
  • Margarita Martí Nicolovius
  • Ester Martínez Membrives
  • Beatriz Molinuevo Alonso
  • Roser Nadal Alemany
  • Jordi Ortiz de Pablo
  • Olga Pol Rigau
  • Albert Quintana Romero
  • Elisenda Sanz Iglesias
  • Carlos Saura Antolín
  • Adolf Tobeña Pallarés
  • Rafael Torrubia Beltri

Goldberg, X., Espelt, C., Palao, D., Nadal, R., & Armario, A. (2020). Adaptability to acute stress among women survivors of intimate partner violence: a protocol for a mixed-methods cross-sectional study in a laboratory setting (BRAW study). BMJ open10(10), e036561. | see post

Labad, J., Salvat-Pujol, N., Armario, A., Cabezas, Á., Arriba-Arnau, AD, Nadal, R.,… & Soria, V. (2020). The Role of Sleep Quality, Trait Anxiety and Hypothalamic-Pituitary-Adrenal Axis Measures in Cognitive Abilities of Healthy Individuals. International journal of environmental research and public health17(20), 7600. | see post

Belda, X., Fuentes, S., Labad, J., Nadal, R., & Armario, A. (2020). Acute exposure of rats to a severe stressor alters the circadian pattern of corticosterone and sensitizes to a novel stressor: Relationship to pre-stress individual differences in resting corticosterone levels. Hormones and Behavior126, 104865. | see post

Armario, A., Labad, J., & Nadal, R. (2020). Focusing attention on biological markers of acute stressor intensity: Empirical evidence and limitations. Neuroscience & Biobehavioral Reviews111, 95-103. | see post

Tost, M., Monreal, JA, Armario, A., Barbero, JD, Cobo, J., García-Rizo, C.,… & Labad, J. (2020). Targeting hormones for improving cognition in major mood disorders and schizophrenia: thyroid hormones and prolactin. Clinical drug investigation40(1), 1-14. | see post

Labad, J., Soria, V., Armario, A., Nadal, R., Monreal, JA, & Palao, D. (2019). Levothyroxine treatment for persistent cognitive symptoms in major depression. Journal of Psychiatry and Mental Health12(3), 199-200. | see post

Labad, J., Armario, A., Nadal, R., Solé, M., Gutiérrez-Zotes, A., Montalvo, I.,… & Vilella, E. (2018). Clinical correlates of hypothalamic-pituitary-adrenal axis measures in individuals at risk for psychosis and with first-episode psychosis. Psychiatry research265, 284-291. | see post

Montalvo, I., Nadal, R., Armario, A., Gutiérrez-Zotes, A., Creus, M., Cabezas, Á.,… & Labad, J. (2018). Sex differences in the relationship between prolactin levels and impaired processing speed in early psychosis. Australian & New Zealand Journal of Psychiatry52(6), 585-595. | see post

The project BioStress, coordinated by Dr. Raül Andero, aims to find biological and psychological biomarkers that can predict the likelihood that a person suffering from a traumatic event will then develop post-traumatic stress disorder and depression.

The project GEPI-BIOPSY, coordinated by Dr. Javier Labad, seeks to determine biomarkers that may be useful in the diagnosis and monitoring of schizophrenia.

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